Subtype Classification of Hepatocellular Adenoma
نویسندگان
چکیده
منابع مشابه
Subtype classification of hepatocellular adenoma.
Hepatocellular adenomas (HCA) are rare benign tumours occurring mainly in women under oral contraceptives. HCA bleed frequently and transform rarely into hepatocellular carcinoma. Identification of genes recurrently mutated in HCA and good genotype/phenotype correlations provided the basis of a pathomolecular classification of different HCA subgroups, characterized using immunohistochemical mar...
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Figure: benign, well-limited hepatocellular tumor with major haemorrhagic foci and telangiectasia on histology. Beside Focal Nodular Hyperplasia and hepatocellular adenomas, the most frequent benign hepatocellular lesion in the liver, a variant, initially called «telangiectatic focal nodular hyperplasia» now claimed as “telangiectatic adenoma” has been described recently. Initially observed in ...
متن کاملManagement of ruptured hepatocellular adenoma.
Hepatocellular adenoma (HA) is an increasingly prevalent benign liver tumor that is strongly associated with use of oral contraceptive medication. The diagnosis is often made after abdominal imaging in female patients with sudden abdominal pain, with or without signs of hemorrhage. Especially larger adenomas are of potential hazard to patients, because of the increased likelihood of rupture or ...
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Hepatocellular adenoma (HCA) is a benign liver tumor composed of hepatocytes. HCA represents a heterogeneous entity, and is subclassified into four groups according to genotype and phenotype: hepatocyte nuclear factor (HNF) 1α-inactivated HCA, β-catenin-activated HCA, inflammatory HCA, and unclassified HCA. Theses subtypes vary greatly in their clinical and pathological features. Identifying th...
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BACKGROUND Hepatocellular adenoma (HCA) is a rare benign tumor of the liver. A subtype classification of HCA (hepatocyte nuclear factor 1α [HNF1α]-mutated, β-catenin-mutated HCA, inflammatory HCA, and unclassified HCA) has recently been established based on a single institutional review of a HCA series by the Bordeaux group. METHODS We used histologic and immunohistochemical parameters to cla...
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ژورنال
عنوان ژورنال: Digestive Surgery
سال: 2010
ISSN: 1421-9883,0253-4886
DOI: 10.1159/000268406